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The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- For side effects caused by lithium: 6 grams of inositol has been taken daily.
- For a grouping of symptoms that increase the risk of diabetes, heart disease, and stroke (metabolic syndrome): 2 grams of a certain form of inositol (isomer myo-inositol) has been taken twice per day for one year.
- For a type of anxiety marked by episodes of intense fear (panic disorder): 12-18 grams of inositol has been taken daily.
- For a hormonal disorder that causes enlarged ovaries with cysts (polycystic ovary syndrome or PCOS): 1000 to 1200 mg of a certain form of inositol (isomer D-chiro-inositol) has been used. Also, a product containing 4 grams of another form of inositol (isomer myo-inositol) plus 400 mcg of folic acid has been taken daily for up to 6 months. A combination of 550 mg of myo-inositol and 150 mg of D-chiro-inositol has also been taken twice daily for up to 12 weeks.
- For preventing preterm birth: 2 grams of a certain form of inositol (isomer myo-inositol) plus 200 mg of folic acid has been taken twice daily throughout pregnancy. 1100 mg of myo-inositol plus 27.6 mg of another form of inositol (isomer D-chiro-inositol) and 400 mg of folic acid has been taken daily throughout pregnancy. *
There are two main forms of inositol used in supplements, namely myo-inositol (MYO) and D-chiro-inositol (DCI).
Though there is no official consensus on the most effective type and dosage, the following have appeared to be effective in research studies:
- For mental health conditions: 12–18 grams of MYO once daily for 4–6 weeks.
- For polycystic ovary syndrome: 1.2 grams of DCI once daily, or 2 grams of MYO and 200 mcg of folic acid twice daily for 6 months.
- For metabolic syndrome: 2 grams of MYO twice daily for one year.
- For blood sugar control in gestational diabetes: 2 grams of MYO and 400 mcg of folic acid twice daily during pregnancy.
- For blood sugar control in type 2 diabetes: 1 gram of DCI and 400 mcg folic acid once daily for 6 months. *