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The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- General: The recommended dietary allowance (RDA) of riboflavin for adults is 1.3 mg per day for males, 1.1 mg per day for women, 1.4 mg per day for pregnant females, and 1.6 mg per day for lactating women. There is no daily Upper Intake Levels (UL) for riboflavin, which is the highest level of intake that is likely to pose no risk of adverse effects.
- For preventing and treating low levels of riboflavin (riboflavin deficiency): Riboflavin 5-30 mg daily has been used.
- For cataracts: A combination of riboflavin 3 mg plus niacin 40 mg daily for 5-6 years has been used.
- For high levels of homocysteine in the blood): Riboflavin 1.6 mg daily for 12 weeks has been used. A combination containing 75 mg of riboflavin, 0.4 mg of folic acid, and 120 mg of pyridoxine daily for 30 days has also been used.
- For migraine headaches: The most common dose is riboflavin 400 mg daily for at least three months. A specific product (Dolovent; Linpharma Inc., Oldsmar, FL ) dosed at two capsules in morning and two capsules in the evening for 3 months has also been used. This dose provides a total of riboflavin 400 mg, magnesium 600 mg, and coenzyme Q10 150 mg per day.
CHILDREN
BY MOUTH:
- General: The recommended dietary allowance (RDA) of riboflavin is 0.3 mg per day for infants up to 6 months old, 0.4 mg per day for infants 6-12 months old, 0.5 mg per day for children 1-3 years old, 0.6 mg per day for children 4-8 years old, 0.9 mg per day for children 9-13 years old, 1.3 mg per day for males 14-18 years old, and 1.0 mg per day for females 14-18. There is no daily Upper Intake Levels (UL) for riboflavin, which is the highest level of intake that is likely to pose no risk of adverse effects.
- For preventing and treating low levels of riboflavin (riboflavin deficiency): Riboflavin 2 mg once, then 0.5-1.5 mg daily for 14 days has been used. Riboflavin 2-5 mg daily for up to two months has been used. Riboflavin 5 mg five days per week for up to one year has also been used. *