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Animal studies have found benefits with ursolic acid in the diet at 0.05-0.2% of the diet, which is around 10-40 mg/kg (based on their weight and food intake) and the estimated human dose equivalent to this is 1.6-6.4 mg/kg bodyweight; for a 150lb adult it would be the range of 110-440 mg.
The lone human study used the higher end of this range, 150 mg three times a day with meals totaling 450 mg each day, and found some biological activity. Until further research arises, thrice daily dosing of 150 mg with meals is recommended. *
