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Studies are lacking to guide clinical applications. Tinctures and the essential oil are used topically for fungal infections. Thyme infusions have been used as a gargle at 5% concentrations.
The pharmacokinetics of thymol in healthy adults have been evaluated. No free thymol was found in the blood or urine, with sulfate and glucuronide metabolites identified in the urine. A mean terminal elimination half-life was estimated to be 10 hours. *