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Dosage recommendations vary depending on the individual, why it’s being used and someone’s level of sensitivity to its effects. Theobromine appears to be safe when used in dosages between 300 to 600 milligrams per day.
When taken long-term, or in higher dosages between 1,000 to 1,500 milligrams, it’s more likely to cause side effects. As little as 1,000 mg/day can also increase your heart rate and worsen symptoms, such as anxiety. *
