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When taken orally, serrapeptase is easily destroyed and deactivated by your stomach acid before it has a chance to reach your intestines to be absorbed.
For this reason, dietary supplements containing serrapeptase should be enteric-coated, which prevents them from being dissolved in the stomach and allows for release in the intestine.
The doses typically used in studies range from 10 mg to 60 mg per day.
The enzymatic activity of serrapeptase is measured in units, with 10 mg equalling 20,000 units of enzyme activity.
You should take it on an empty stomach or at least two hours before eating. In addition, you should avoid eating for about half an hour after taking serrapeptase. *
