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The lowest active supplemental dose appears to be 300mg, and supplementation above this dose appears to confer dose-dependent effects although it is not very reliable (ie. one study says that 1200mg gives thrice as much benefit as 300mg while another suggests 1.4x benefit)
Lemon Balm bioactives may also be consumed via tea or acquired via aromatherapy, although it is much harder to quantify 'the right dose' via these two methods. *
The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- For Alzheimer disease: 60 drops per day of a standardized lemon balm extract has been used for 4 months.
- For anxiety: 300 mg of a standardized lemon balm extract (Cyracos by Naturex SA) taken twice daily for 15 days has been used. Also 0.23 mL/kg body weight of a combination product containing 13 ingredients including lemon balm (Klosterfrau Melissengeist, Klosterfrau) taken three times daily for 8 weeks has been used.
- For insomnia: 300 mg of a standardized lemon balm extract (Cyracos by Naturex SA) has been used twice daily for 15 days. Also, a specific combination product containing 80 mg of lemon balm leaf extract and 160 mg of valerian root extract (Euvegal forte, Dr. Willmar Schwabe Pharmaceuticals) has been taken 2-3 times daily for up to 30 days. Also, tablets containing 170 mg of valerian root, 50 mg of hops, 50 mg of lemon balm, and 50 mg of motherwort have been used. Three capsules containing 1000 mg of lemon balm and 400 mg of Nepeta menthoides have also been taken nightly for 4 weeks.
- For stress: Many different doses have been studied in scientific research. A single dose of 600 mg of lemon balm extract during a stress test has been used. Also, a single dose of 300 mg of lemon balm extract (Bluenesse by Vital Solutions) has been added to food or drink and used during a mental test. Also, three tablets of a specific product containing 80 mg of lemon balm extract and 120 mg of valerian root extract per tablet (Songha Night by Pharmaton Natural Health Products) have been taken before a stress test. Also, a specific combination product containing 90 mg of passion flower, 90 mg of valerian root, 50 mg of lemon balm, and 90 mg of butterbur per tablet (Relaxane, Max Zeller Söhne AG) has been taken as one tablet three times daily for 3 days.
APPLIED TO THE SKIN:
- For cold sores (herpes labialis): Cream containing 1% lemon balm extract (LomaHerpan by Infectopharm) has been applied 2-4 times daily. It is usually applied at the first sign of symptoms to a few days after the cold sores have healed.
CHILDREN
BY MOUTH:
- For insomnia: 1-2 tablets of a specific combination product containing 80 mg of lemon balm leaf extract and 160 mg of valerian root extract (Euvegal forte, Dr. Willmar Schwabe Pharmaceuticals) has been taken once or twice daily in children under 12 years-old. *