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The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- For L-carnitine deficiency: 990 mg two to three times daily in tablets or as an oral solution.
- For chest pain (angina): Doses of 900 mg to 2 grams of L-carnitine have been taken in one to two divided doses daily for 2 weeks to 6 months.
- For heart failure and fluid build up in the body (congestive heart failure or CHF): 1.5 to 3.0 grams of L-carnitine has been taken in one to two divided doses daily for up to about 34 months. A specific product (Carni Q-Gel, Tishcon Corporation) containing 2250 mg of carnitine and 270 mg of coenzyme Q10 has been taken daily for 12 weeks.
- For serious kidney disease (end-stage renal disease or ESRD): Doses of 0.64-3 grams or 10 mg/kg of L-carnitine has been used daily for 3-52 weeks. Taking L-carnitine by mouth is not FDA approved to treat carnitine deficiency in people with serious kidney disease.
- For overactive thyroid (hyperthyroidism): 2-4 grams of L-carnitine has been taken daily for 2-4 months.
- For conditions in a man that prevent him from getting a woman pregnant within a year of trying to conceive (male infertility): 2-3 grams of L-carnitine has been taken in up to three divided doses daily, with or without vitamin E, for 2 to 24 weeks. Also, 2 grams of L-carnitine plus 1 gram of acetyl-L-carnitine has been taken daily, with or without a 300 mg cinnoxicam suppository every 4 days, for 3-6 months. A specific product (Proxeed Plus, Alfasigma USA) containing L-carnitine 1 gram and acetyl-L-carnitine 0.5 gram, with citric acid, zinc, coenzyme Q10, selenium, vitamin C, folic acid, and vitamin B12, twice daily for 6 months.
- For swelling (inflammation) of the heart (myocarditis): 100 mg/kg of D,L-carnitine has been taken daily for 4 days.
- For a hormonal disorder that causes enlarged ovaries with cysts (polycystic ovary syndrome or PCOS): 250 mg of L-carnitine has been taken daily for 12 weeks. 3-4 grams of L-carnitine have been taken daily during clomiphene treatment starting at day 3 of the cycle and ending within 2-3 weeks. L-carnitine 3 grams daily for 3 months has also been used.
- For toxic side effects caused by the drug valproic acid: 50 to 100 mg/kg has been taken in three or four divided doses daily up to a maximum of 3 grams daily. *
