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In the past, it was assumed that it is impossible to supplement since the body breaks down proteins in the digestive process and oral glutathione would not be absorbed.
New forms, like liposomal glutathione, solve this problem, but it is still important to consume a nutrient rich diet that includes the building blocks of glutathione (especially from leafy greens and onions/garlic). I actually use a topical glutathione spray transdermally (on the skin) over my thyroid and it seems to help.
The supplement N-Acetyl-L-Cysteine is shown to naturally increase the body’s production and there is some evidence that Vitamin C can help protect glutathione levels.
Some naturopathic doctors provide intravenous glutathione injections. This is an effective way to boost levels, though not available in many places. *
