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The following doses have been studied in scientific research:
BY MOUTH:
- For osteoarthritis: The typical dose of chondroitin sulfate is 800-2000 mg taken as a single dose or in two or three divided doses daily for up to 3 years.
APPLIED TO THE SKIN:
- For osteoarthritis: A cream containing 50 mg/gram of chondroitin sulfate, 30 mg/gram of glucosamine sulfate, 140 mg/gram of shark cartilage, and 32 mg/gram of camphor has been used as needed for sore joints for up to 8 weeks.
INJECTED INTO THE MUSCLE:
- For osteoarthritis: Chondroitin sulfate (Matrix) has been injected into the muscle daily or twice weekly for 6 months.
APPLIED TO THE EYE:
- For cataracts: Several different eye drops containing sodium hyaluronate and chondroitin sulfate (DisCoVisc, Alcon Laboratories; Viscoat, Alcon Laboratories; DuoVisc, Alcon Laboratories; Viscoat, Alcon Laboratories; Provisc, Alcon Laboratories) have been used during cataract surgery. *
Chondroitin sulfate is available in capsules, tablets, and powders. The typical dosage used in clinical trials was between 800 and 2,000 milligrams (mg) per day, taken in two to three divided doses. Although the supplement can be taken with or without food, it may be better with food if you experience stomach upset.
There are also co-formulated topical ointments containing chondroitin sulfate and other ingredients (such as glucosamine, camphor, and shark cartilage) that are marketed for joint pain relief. While considered safe, there is no evidence that any of these topical products work. *
