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The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
- General: One cup of brewed coffee provides from 95-200 mg of caffeine. An 8-ounce serving of black tea provides from 40-120 mg of caffeine. An 8-ounce serving of green tea provides 15-60 mg of caffeine. Soft drinks such as cola provide from 20-80 mg of caffeine per 12 ounce serving. Sports or energy drinks typically provide from 48-300 mg of caffeine per serving.
- For headache: Does of 100-250 mg caffeine daily have been used. Caffeine has also been used together with acetaminophen, aspirin, ergotamine, and sumatriptan.
- For headache after epidural anesthesia: Caffeine 300 mg has been used.
- For mental alertness: Doses of 100-600 mg caffeine daily have been used. Caffeine has also been taken together with taurine, glucose and L-theanine.
- For asthma: Caffeine has been taken in doses of 9 mg/kg.
- For improving athletic performance: 2-10 mg/kg has been used. Keep in mind that doses in excess of 800 mg per day can result in urine levels greater than the 15 mcg/mL allowed by the National Collegiate Athletic Association.
- For preventing gallstone disease: Consumption of 400 mg or more of caffeine daily has been used.
- For memory: 65-200 mg of caffeine has been used.
- For obesity: Ephedrine/caffeine combination products are commonly dosed 20 mg/200 mg three times daily. A specific combination product (Prograde Metabolism) containing 1000 mg of a combination of raspberry ketone, caffeine, capsicum extract, garlic root extract, ginger root extract, bitter orange fruit, L-theanine, and black pepper fruit extract has been used twice daily for 8 weeks.
- For pain: Doses of 50-130 mg caffeine have been used with pain relievers including acetaminophen, propyphenazone, and ibuprofen.
- For preventing Parkinson disease: Men drinking 421-2716 mg of total caffeine daily have the lowest risk of developing Parkinson disease, when compared to other men. However, men who drink as little as 124-208 mg of caffeine daily also have a significantly lower chance of developing Parkinson disease. In women, moderate caffeine intake per day (1-3 cups of coffee per day) seems to be best.
BY IV:
- Headache after surgery: 200 mg of caffeine has been given intravenously to prevent headache after surgery.
CHILDREN
BY MOUTH:
- For breathing problems in premature infants (neonatal apnea): Caffeine is given by mouth to infants by healthcare providers for this condition.
BY IV:
- For a lung disease that affects newborns (bronchopulmonary dysplasia): Caffeine is given intravenously (by IV) by healthcare providers for this condition.
- For headache after epidural anesthesia: Caffeine is given intravenously (by IV) by healthcare providers for this condition. *
